Is allograft a more reliable treatment option than autograft in 2-level anterior cervical discectomy and fusion with plate fixation?
Jin-Sung Park, MDa,b, Se-Jun Park, MDa,∗, Chong-Suh Lee, MD, PhDa, Sung-Soo Chung, MD, PhDa, Hyun-Jin Park, MDa
This study aimed to assess the efficacy of allograft in 2-level anterior cervical discectomy and fusion (ACDF) with plate fixation by comparing its clinical and radiological outcomes to those of autograft.
Thirty five patients with femur cortical allografts and 32 patients with tricortical iliac autografts were evaluated. All surgeries were performed by a single senior surgeon. During routine follow-up (at 3 months, 6 months, and annually after the surgery), the fusion rate, subsidence rate, and fused segmental lordosis angle were assessed by radiologic evaluation. Clinical outcomes were assessed using the visual analog scale (VAS), neck disability index (NDI) scores, and Odom criteria. This study was conducted using the results of the2-year postoperative follow-up. Among 67 patients, 62 (92.5%) showed successful bone fusion at 2 years postoperatively: 91.4% (32/35) in the allograft group and 93.8% (30/32) in the autograft group.
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